Nordic Papers (1 December 2021)

A curated list of scholarly publications relevant to research, policy and health care from the Nordic human genetics and precision medicine community and their collaborators.

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Nordic Papers List (Most Recent First):

A combined genome-wide association and molecular study of age-related hearing loss in H. sapiens.
Liu W, Johansson Å, Rask-Andersen H, Rask-Andersen M.
BMC Med. 2021 Dec 1;19(1):302.

Cardiovascular Family History Increases the Risk of Disease Recurrence After a First Myocardial Infarction.
Wahrenberg A, Kuja-Halkola R, Magnusson PKE, Häbel H, Warnqvist A, Hambraeus K, Jernberg T, Svensson P.
J Am Heart Assoc. 2021 Nov 30:e022264.

The role of growth and nutrition in the early origins of spirometric restriction in adult life: a longitudinal, multicohort, population-based study.
Voraphani N, Stern DA, Zhai J, Wright AL, Halonen M, Sherrill DL, Hallberg J, Kull I, Bergström A, Murray CS, Lowe L, Custovic A, Morgan WJ, Martinez FD, Melén E, Simpson A, Guerra S.
Lancet Respir Med. 2021 Nov 26:S2213-2600(21)00355-6.

Oxytocin-pathway polygenic scores for severe mental disorders and metabolic phenotypes in the UK Biobank.
Winterton A, Bettella F, de Lange AG, Haram M, Steen NE, Westlye LT, Andreassen OA, Quintana DS.
Transl Psychiatry. 2021 Nov 25;11(1):599.

Comparing Copy Number Variations in a Danish Case Cohort of Individuals With Psychiatric Disorders.
Calle Sánchez X, Helenius D, Bybjerg-Grauholm J, Pedersen C, Hougaard DM, Børglum AD, Nordentoft M, Mors O, Mortensen PB, Geschwind DH, Montalbano S, Raznahan A, Thompson WK, Ingason A, Werge T.
JAMA Psychiatry. 2021 Nov 24.

Open science and sharing personal data widely - legally impossible for Europeans?
Ursin G, Bentzen HB.
Acta Oncol. 2021 Nov 19:1-2.

Novel disease associations with schizophrenia genetic risk revealed in ~400,000 UK Biobank participants.
Zhang R, Sjölander A, Ploner A, Lu D, Bulik CM, Bergen SE.
Mol Psychiatry. 2021 Nov 19.

Instrumental variable analysis using offspring BMI in childhood as an indicator of parental BMI in relation to mortality.
Blond K, Carslake D, Gjærde LK, Vistisen D, Sørensen TIA, Smith GD, Baker JL.
Sci Rep. 2021 Nov 17;11(1):22408.

The Effect of General Adiposity and Central Body Fat Distribution on the Circulating Metabolome: a Multi-Cohort Non-Targeted Metabolomics Observational and Mendelian Randomization Study.
Ahmad S, Hammar U, Kennedy B, Salihovic S, Ganna A, Lind L, Sundström J, Ärnlöv J, Berne C, Risérus U, Magnusson PK, Larsson SC, Fall T.
Diabetes. 2021 Nov 16:db201120.

Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health.
Johannessen J, Nærland T, Hope S, Torske T, Kaale A, Wirgenes KV, Malt E, Djurovic S, Rietschel M, Andreassen OA.
Eur J Hum Genet. 2021 Nov 15.

Comprehensive biomarker profiling of hypertension in 36,985 Finnish individuals.
Palmu J, Tikkanen E, Havulinna AS, Vartiainen E, Lundqvist A, Ruuskanen MO, Perola M, Ala-Korpela M, Jousilahti P, Würtz P, Salomaa V, Lahti L, Niiranen T.
J Hypertens. 2021 Nov 15.

Pleiotropy between language impairment and broader behavioral disorders-an investigation of both common and rare genetic variants.
Nudel R, Appadurai V, Buil A, Nordentoft M, Werge T.
J Neurodev Disord. 2021 Nov 13;13(1):54.

Genetic Predisposition to Mosaic Chromosomal Loss Is Associated With Functional Outcome After Ischemic Stroke.
Johansson M, Pedersen A, Cole JW, Lagging C, Lindgren A, Maguire JM, Rost NS, Söderholm M, Worrall BB, Stanne TM, Jern C.
Neurol Genet. 2021 Nov 12;7(6):e634.

Discordant associations of educational attainment with ASD and ADHD implicate a polygenic form of pleiotropy.
Verhoef E, Grove J, Shapland CY, Demontis D, Burgess S, Rai D, Børglum AD, St Pourcain B.
Nat Commun. 2021 Nov 11;12(1):6534.

Proteins associated with incident metabolic syndrome in population-based cohorts.
Lind L, Sundström J, Ärnlöv J.
Diabetol Metab Syndr. 2021 Nov 10;13(1):131.

Elevated circulating follistatin associates with an increased risk of type 2 diabetes.
Wu C, Borné Y, Gao R, López Rodriguez M, Roell WC, Wilson JM, Regmi A, Luan C, Aly DM, Peter A, Machann J, Staiger H, Fritsche A, Birkenfeld AL, Tao R, Wagner R, Canouil M, Hong MG, Schwenk JM, Ahlqvist E, Kaikkonen MU, Nilsson P, Shore AC, Khan F, Natali A, Melander O, Orho-Melander M, Nilsson J, Häring HU, Renström E, Wollheim CB, Engström G, Weng J, Pearson ER, Franks PW, White MF, Duffin KL, Vaag AA, Laakso M, Stefan N, Groop L, De Marinis Y.
Nat Commun. 2021 Nov 10;12(1):6486.

DeepFake electrocardiograms using generative adversarial networks are the beginning of the end for privacy issues in medicine.
Thambawita V, Isaksen JL, Hicks SA, Ghouse J, Ahlberg G, Linneberg A, Grarup N, Ellervik C, Olesen MS, Hansen T, Graff C, Holstein-Rathlou NH, Strümke I, Hammer HL, Maleckar MM, Halvorsen P, Riegler MA, Kanters JK.
Sci Rep. 2021 Nov 9;11(1):21896.

Life-time Actionable Pharmacogenetic Drug Use: A Population-based Cohort Study in 86,040 Young People With and Without Mental Disorders in Denmark.
Lunenburg CATC, Ishtiak-Ahmed K, Werge T, Gasse C.
Pharmacopsychiatry. 2021 Nov 9.

Coagulation parameters in the newborn and infant - the Copenhagen Baby Heart and COMPARE studies.
Nielsen ST, Strandkjær N, Juul Rasmussen I, Hansen MK, Lytsen RM, Kamstrup PR, Rode L, Goetze JP, Iversen K, Bundgaard H, Frikke-Schmidt R.
Clin Chem Lab Med. 2021 Nov 9.

Risk of lower respiratory tract infections: A genome-wide association study with Mendelian randomization analysis in three independent European populations.
Flatby HM, Rasheed H, Ravi A, Thomas LF, Liyanarachi KV, Afset JE, DeWan AT, Brumpton BM, Hveem K, Åsvold BO, Simonsen GS, Furberg AS, Damås JK, Solligård E, Rogne T.
Clin Microbiol Infect. 2021 Nov 8:S1198-743X(21)00631-5.

MicroRNA profiling of psoriatic skin identifies 11 miRNAs associated with disease severity.
Solvin ÅØ, Chawla K, Olsen LC, Hegre SA, Danielsen K, Jenssen M, Furberg AS, Saunes M, Hveem K, Saetrom P, Løset M.
Exp Dermatol. 2021 Nov 8.

Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders.
Eijsbouts C, Zheng T, Kennedy NA, Bonfiglio F, Anderson CA, Moutsianas L, Holliday J, Shi J, Shringarpure S; 23andMe Research Team, Voda AI; Bellygenes Initiative, Farrugia G, Franke A, Hübenthal M, Abecasis G, Zawistowski M, Skogholt AH, Ness-Jensen E, Hveem K, Esko T, Teder-Laving M, Zhernakova A, Camilleri M, Boeckxstaens G, Whorwell PJ, Spiller R, McVean G, D'Amato M, Jostins L, Parkes M.
Nat Genet. 2021 Nov;53(11):1543-1552. Epub 2021 Nov 5.

Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes.
Mansour Aly D, Dwivedi OP, Prasad RB, Käräjämäki A, Hjort R, Thangam M, Åkerlund M, Mahajan A, Udler MS, Florez JC, McCarthy MI; Regeneron Genetics Center, Brosnan J, Melander O, Carlsson S, Hansson O, Tuomi T, Groop L, Ahlqvist E.
Nat Genet. 2021 Nov;53(11):1534-1542. Epub 2021 Nov 4.

Towards improved precision and a new classification of diabetes mellitus.
Ahlqvist E, Prasad RB, Groop L.
J Endocrinol. 2021 Nov 1:JOE-20-0596.R1.

Diet and Lifestyle Factors and Risk of Atherosclerotic Cardiovascular Disease-A Prospective Cohort Study.
Acosta S, Johansson A, Drake I.
Nutrients. 2021 Oct 27;13(11):3822.

Reaction Time and Visual Memory in Connection to Hazardous Drinking Polygenic Scores in Schizophrenia, Schizoaffective Disorder and Bipolar Disorder.
Mazumder AH, Barnett J, Isometsä ET, Lindberg N, Torniainen-Holm M, Lähteenvuo M, Lahdensuo K, Kerkelä M, Ahola-Olli A, Hietala J, Kampman O, Kieseppä T, Jukuri T, Häkkinen K, Cederlöf E, Haaki W, Kajanne R, Wegelius A, Männynsalo T, Niemi-Pynttäri J, Suokas K, Lönnqvist J, Tiihonen J, Paunio T, Vainio SJ, Palotie A, Niemelä S, Suvisaari J, Veijola J.
Brain Sci. 2021 Oct 27;11(11):1422.

Placental weight centiles adjusted for age, parity and fetal sex.
Flatley C, Sole-Navais P, Vaudel M, Helgeland Ø, Modzelewska D, Johansson S, Jacobsson B, Njølstad P.
Placenta. 2021 Oct 23;117:87-94.

Governing health data across changing contexts: A focus group study of citizen's views in England, Iceland, and Sweden.
Shah N, Viberg Johansson J, Haraldsdóttir E, Bentzen HB, Coy S, Mascalzoni D, Jónsdóttir GA, Kaye J.
Int J Med Inform. 2021 Dec;156:104623. Epub 2021 Oct 21. Review.